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  • Title: [Early changes in the nucleoside diphosphate kinase activity of the rat brain and liver during whole body gamma irradiation in an absolutely lethal dose].
    Author: Savitskiĭ IV, Nagiev ER.
    Journal: Radiobiologiia; 1983; 23(2):237-40. PubMed ID: 6302731.
    Abstract:
    Nucleoside diphosphatkinase activity in mitochondria and post-mitochondrial supernatant fraction from brain and liver tissues was shown to decrease sharply during the first 60 min after total-body gamma-irradiation of rats with an absolutely lethal dose (30 Gy). A significant increase in the enzyme activity was registered 3 and 24 h following irradiation. Changes in nucleoside diphosphatkinase activity were more pronounced in mitochondria (particularly in liver mitochondria) than in the supernatant fraction.
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