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  • Title: Ionizing radiation decreases veratridine-stimulated uptake of sodium in rat brain synaptosomes.
    Author: Wixon HN, Hunt WA.
    Journal: Science; 1983 Jun 03; 220(4601):1073-4. PubMed ID: 6302846.
    Abstract:
    Veratridine-stimulated uptake of sodium-22 in brain synaptosomes was significantly reduced by ionizing radiation over a dose range of 10 to 1000 rads. The response was dose-dependent and involved a decrease in the maximum effect of veratridine on uptake. The central nervous system may be more sensitive to ionizing radiation than generally thought, perhaps through a loss of the ability of the sodium channel to respond properly to stimulation.
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