These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Panax ginseng and Eleuthrococcus senticosus extracts--in vitro studies on binding to steroid receptors.
    Author: Pearce PT, Zois I, Wynne KN, Funder JW.
    Journal: Endocrinol Jpn; 1982 Oct; 29(5):567-73. PubMed ID: 6303763.
    Abstract:
    We have examined the binding of 44% saponin from Panax ginseng, and extracts from Eluthrococcus senticosus (Siberian ginseng) to classical steroid receptors in vitro. Both extracts had demonstrable affinity for progestin, mineralocorticoid and glucocorticoid receptors; the Siberian ginseng also bound to estrogen receptors. Highest affinity binding was to glucocorticoid receptors, with an approximate Ki of 8 x 10(-6) M for Panax ginseng. Such interactions may explain the reported glucocorticoid-like effects of ginseng in vivo.
    [Abstract] [Full Text] [Related] [New Search]