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  • Title: [Effect of opioid peptides on the transmission of nociceptive excitation in the spinal cord afferent tracts].
    Author: Kasparov SA.
    Journal: Farmakol Toksikol; 1983; 46(2):40-4. PubMed ID: 6303837.
    Abstract:
    The effects of methionine-enkephalin, leucine-enkephalin and of their two synthetic analogs on nociceptive transmission in the afferent tract of the spinal cord were studied in anesthetized spinal rats. All the opioid peptides inhibited the bradykinin-induced discharges in axons of the ventrolateral tract. However, the preparations had dissimilar effects on spontaneous activity. Naloxone blocked the action of the opioids.
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