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  • Title: [Practical value of the determination of urinary fibrin degradation products in the early management of renal transplants].
    Author: André E, Kessler M, Briquel ME, Alexandre P, Hurault de Ligny B, Huriet C.
    Journal: Sem Hop; 1983 Jun 02; 59(22):1669-73. PubMed ID: 6308788.
    Abstract:
    We studied daily urinary excretion of fibrin degradation products (UFDP) during the first month following renal transplantation in 31 patients using the Merskey technique. After the 48 first hours a rise of UFDP was observed in 3 circumstances: 1) acute rejection: twenty-four acute rejections were observed in twenty-two patients. The increase of UFDP was constant. It preceeded the clinical diagnosis of rejection in 63 p. 100 of the patients. It has a predictive value in all cases. 2) Severe urinary infection. In 5 patients with urologic complications UFDP rose markedly. 3) Macroscopic hematuria. In 2 patients with gross hematuria very high rates of excretion were observed.
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