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  • Title: [Serum activity of angiotensin converting enzyme during extracorporeal circulation in man].
    Author: Faymonville ME, Larbuisson R, Radermecker M, Limet R, Fourny J, Lamy M.
    Journal: C R Seances Soc Biol Fil; 1983; 177(2):252-8. PubMed ID: 6309338.
    Abstract:
    Serum activity of angiotensin converting enzyme (ACE) were measured during extra-corporeal circulation in five patients undergoing aorto-coronary bypass surgery. We observed a significant decrease of serum ACE levels in the absence of pulmonary circulation, suggesting that in man the lungs were the major source of circulating ACE. An effective extra-pulmonary liberation of ACE could take place during cardiopulmonary bypass. The levels of serum ACE increased with pulmonary recirculation, but preoperative levels were not reached 24 h later.
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