These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Inherited susceptibility to retrovirus-induced transformation of Gardner syndrome cells.
    Author: Rasheed S, Rhim JS, Gardner EJ.
    Journal: Am J Hum Genet; 1983 Sep; 35(5):919-31. PubMed ID: 6310993.
    Abstract:
    Skin fibroblasts from patients with Gardner syndrome (GS), those with familial polyposis coli (FPC), and spouse or unrelated controls were karyotyped and tested for various growth properties including susceptibility to transformation by viral or chemical agents. Our results indicated that based on the higher susceptibility to retrovirus-induced transformation and chromosomal aneuploidy, the GS and FPC cells could be distinguished from those of the general population with more than 70% accuracy. However, much work is in order before any biological assay can be used for clinical diagnosis of GS or FPC patients.
    [Abstract] [Full Text] [Related] [New Search]