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  • Title: Perioperative use of ceftazidime as a prophylactic agent in transurethral surgery.
    Author: Childs SJ, Mirelman S, Wells WG.
    Journal: J Antimicrob Chemother; 1983 Jul; 12 Suppl A():71-6. PubMed ID: 6311789.
    Abstract:
    Sixty-eight patients undergoing transurethral surgery were randomly assigned to receive either a single dose of ceftazidime (31 patients) preoperatively, or three doses of cefotaxime (34 patients) perioperatively, as prophylaxis. In this study, only 1/20 male patients (5%), and none of the female patients, developed an infection. We conclude that single-dose prophylaxis, with a safe, broad-spectrum antimicrobial, provides adequate protection against postoperative infection in genitourinary surgery.
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