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  • Title: [New contributions on extinction tests of essential headache. I. The test with lysine acetylsalicylate].
    Author: Romiti A, Martelletti P, Gallo MF, Perrotta RA, Giacovazzo M.
    Journal: Boll Soc Ital Biol Sper; 1983 Aug 30; 59(8):1130-3. PubMed ID: 6313019.
    Abstract:
    We report some preliminary results of a study carried out in ten patients observed during headache attack and concerning particularly the plasma values of beta-ELI after acetylsalicylic acid (lysini acetylsalicylas: i.v. 1.8 g) administration. Blood samples for beta-ELI determination were drawn every ten minutes for 30 minutes beginning at time of drug administration. Plasma was immediately separated and stored at -20 degrees C until assayed. Lysini acetylsalicylas administration gave in our subjects a significant relief from pain, with a disappearance of headache in all cases. We showed, in comparison with basal conditions, increased-plasma beta-ELI values after drug administration. The levels of pain were evaluated by the analogic visual scale.
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