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  • Title: Portal hypertension in systemic mastocytosis.
    Author: Capron JP, Lebrec D, Degott C, Chivrac D, Coevoet B, Delobel J.
    Journal: Gastroenterology; 1978 Mar; 74(3):595-7. PubMed ID: 631492.
    Abstract:
    We report the case of a 66-year-old male patient with portal hypertension related to systemic mastocytosis. The liver was enlarged; microscopic examination showed portal mast cell infiltration and fibrosis. Portal hypertension was evidenced by splenomegaly, esophageal varices, and increased wedged-free hepatic venous pressure gradient. Arteriography showed that portal vein was patent. Portal hypertension could be the consequence of intrahepatic block due to mast cell infiltration and/or fibrosis of the liver.
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