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  • Title: Cholecystokinin-octapeptide-induced hyperthermia in guinea-pigs.
    Author: Kandasamy SB, Williams BA.
    Journal: Experientia; 1983 Nov 15; 39(11):1282-4. PubMed ID: 6315476.
    Abstract:
    Intracerebroventricular administration of cholecystokinin-octapeptide (CCK-8) at room temperature (21 degrees C) induced dose-related hyperthermia in guinea-pigs and also produced hyperthermia at low (10 degrees C) and high (30 degrees C) ambient temperatures. CCK-8-induced hyperthermia was direct and not mediated by prostaglandins, norepinephrine, cyclic AMP or naloxone-sensitive receptors.
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