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  • Title: ELISA antibodies to cytomegalovirus in pregnant patients: prevalence in and correlation with spontaneous abortion.
    Author: Luerti M, Santini A, Bernini O, Castiglioni M, Ragni MC.
    Journal: Biol Res Pregnancy Perinatol; 1983; 4(4):181-3. PubMed ID: 6317066.
    Abstract:
    Prevalence of seroimmunity to cytomegalovirus (CMV) infection was tested by detecting ELISA IgG antibodies in 230 pregnant subjects from low socioeconomic backgrounds. Seroimmunity increased from 64.3% to 92.0% between the ages 15-20 and 35-40. Furthermore, ELISA IgM antibodies were detected during hospitalization in a group of 56 women whose pregnancies ended in spontaneous abortion and in a paired matched-control group. The overall percentage of IgM-positive reactions was 5.35% in the group with abortion. The percentage for only second trimester abortions amounted to 18.75%. There was no IgM-positive reaction in the control group.
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