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  • Title: [Beta-adrenergic mechanism of the radio-protective effect of isoproterenol in a mammalian cell culture].
    Author: Chirkov IuIu, Babiĭ NI, Sobolev AS.
    Journal: Radiobiologiia; 1983; 23(6):819-22. PubMed ID: 6318258.
    Abstract:
    A specific beta-agonist, isoproterenol, increased the intracellular content of cyclic AMP and decreased the radiosensitivity of Chinese hamster fibroblasts. Beta-antagonist, propranolol, blocked the manifestation of the effect of isoproterenol. Isoproterenol did not affect either the intracellular level of cyclic AMP or the radiosensitivity of B-82 cells which had no beta-adrenoreceptors.
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