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  • Title: [Comparative double-blind study of ketoprofen slow-release tablets and indomethacin in coxarthrosis and gonarthrosis].
    Author: Gougeon J.
    Journal: Sem Hop; 1983 Dec 12; 59(46):3246-8. PubMed ID: 6318352.
    Abstract:
    This comparative trial, in which each patient acts as his own control, is an ideal model for comparing the effectiveness of both products. None of the criteria studied demonstrated a statistically significant difference in effectiveness between the two agents. Under the conditions of this study, Bi-Profenid and indomethacin can therefore be considered as having comparable potency. Study of tolerance demonstrated a superiority of Bi-Profenid over indomethacin, with excellent results in 72.5% and 66.1% of cases respectively. Specifically, digestive and above all neuro-sensory tolerance was better with Bi-Profenid. Osteoarthritis is a good indication for these medications whose effectiveness is well documented.
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