These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Diethyldithiocarbamate depresses the acoustic startle response in rats.
    Author: Storm JE, Millington WR, Fechter LD.
    Journal: Psychopharmacology (Berl); 1984; 82(1-2):68-72. PubMed ID: 6320250.
    Abstract:
    The relationship between norepinephrine (NE) content in cortex and spinal cord and acoustic startle amplitude was investigated in two experiments. Administration of diethyldithiocarbamate (DDC) depressed startle amplitude at the same time and dose that it most severely depleted NE content. These results support the conclusion that NE facilitates the normal elaboration of the acoustic startle reflex and also support evidence that NE activity in the spinal cord may be of particular importance in the maintenance of normal startle amplitude.
    [Abstract] [Full Text] [Related] [New Search]