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  • Title: [Isolation of enteroviruses from patients with clinical manifestations of poliomyelitis].
    Author: Spynu KI, Vutkarev VP.
    Journal: Vopr Virusol; 1983; 28(6):686-9. PubMed ID: 6322453.
    Abstract:
    Examinations of 114 specimens (feces, nasopharyngeal washings, cerebrospinal fluid) from patients with clinical manifestations of poliomyelitis were carried out. Enteroviruses were isolated in 61.4% of the cases. Among the isolates, poliomyelitis viruses accounted for 49.1%, and Coxsackie B1 and ECHO 6 12.3%. Typing of the poliovirus isolates showed 17.9% to belong to type I, 7.1% to type II, and 75% to type III. Studies on intratypic differentiation revealed their antigenic similarity with the Mahoney, MEF-1, and Saukett strains, respectively. Among 24 paired blood sera tested for virus-neutralizing antibodies to wild poliovirus strains 21 demonstrated a 4-fold or higher rise of antibody titres to the above poliomyelitis viruses.
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