These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: [Possible participation of a free-radical lipid intermediate in the hydroxylation of polycyclic hydrocarbons].
    Author: Dmitriev LF, Belevich NP, Davletshina LN, Ivanov II.
    Journal: Biokhimiia; 1983 Dec; 48(12):2041-8. PubMed ID: 6322866.
    Abstract:
    The effects of pro-oxidants (Fe2+, CCl4) and antioxidants (alpha-tocopherol, propyl gallate) on hydroxylation of polycyclic hydrocarbon benz(a)pyrene and on the NADPH-cytochrome P-450-reductase reaction were studied. The role of allyl radicals formed in the fatty acid chains in discussed. The binding of O2 to free radicals, i. e. formation of peroxy radicals, is regarded only as a possible reaction of the radical utilization. It is assumed that other reactions involving lipid radicals, in particular, electron transfer from the flavoprotein to cytochrome P-480 may occur in microsomal membranes.
    [Abstract] [Full Text] [Related] [New Search]