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  • Title: DNA supercoiling by core histone fractions and protamine.
    Author: Vashakidze RP, Karpenchuk KG, Undritsov IM, Naktinis VI.
    Journal: Mol Biol Rep; 1984 Jan; 9(4):259-62. PubMed ID: 6323967.
    Abstract:
    The nuclear extract isolated from late Drosophila melanogaster embryos has Mg2+-dependent DNA topoisomerase 1 and nuclease activities. The extract facilitates the closed circular duplex DNA supercoiling in the presence of calf histone fractions H2A, H2B, H3 and H4, and fish protamine but not HI histone.
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