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Title: Stimulation of the Na/K pump in LK sheep erythrocytes by immunoglobulin fragments. Author: Bratcher RL, Kanik-Ennulat CL, Logue PJ, Dunham PB. Journal: Immunol Commun; 1983; 12(6):565-71. PubMed ID: 6325329. Abstract: Alloimmune antiserum against the L antigen of red cells from sheep of the LK phenotype is known to stimulate by several fold active Na/K transport in LK cells. We have shown that monomeric fragments, Fab1, of anti-L, as well as dimeric fragments, F(ab1)2, stimulate transport to the same extent as intact anti-L Ig. Special care was taken to obtain pure fragments. Two earlier reports on the effect of immunoglobulin fragments were contradictory.[Abstract] [Full Text] [Related] [New Search]