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  • Title: [Genital hemorrhage in girls before puberty. Apropos of 33 cases].
    Author: David L, Betend B, Berlier P, Evrard A, Guinard A, François R.
    Journal: Sem Hop; 1984 Apr 19; 60(17):1195-9. PubMed ID: 6326314.
    Abstract:
    Vaginal bleeding in young girls without other signs of precocious sexual development is rare. We report a series of 33 cases observed during a 21 year period in the departments of pediatrics of the University of Lyon. Among the various etiologies, vaginal foreign bodies (10 cases, 30%) and vaginitis (10 cases, 30%) were the most frequent. There were 3 cases of benign vulvar tumors (9%) and 3 cases of malignant vaginal tumors (9%). In 3 cases the vaginal bleeding remained apparently idiopathic leading to the diagnosis of premature menarche. A retrospective evaluation of each case showed that history, physical examination and colposcopy would have rapidly established the correct diagnosis in 80 to 85% of cases; it is therefore concluded that laboratory and complex gynecologic investigations should be considered only after negative findings from these simple clinical tools in the evaluation of vaginal bleeding in prepubertal girls.
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