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  • Title: Immunological identification of peripheral-blood lymphocytes from patients with lymphoproliferative disorders in Nigeria. I. Acute lymphocytic leukaemia (ALL).
    Author: Ukaejiofo EO, Sagoe AS, Osunkoya BO.
    Journal: Afr J Med Med Sci; 1983; 12(3-4):187-95. PubMed ID: 6326553.
    Abstract:
    The peripheral-blood lymphocytes of eight consecutively diagnosed cases of acute lymphocytic leukaemia (ALL) in Nigerians seen over a period of 2 years were classified as T, B and Null cells, using mainly sheep-rosetting (for T cells) and EAC-rosetting (for B cells) techniques. The patients' lymphocytes response to stimulation with phytohaemagglutinin (PHA) and basic haematological parameters were also determined. There were three male cases (37.5%), aged 10, 14 and 21 years who had T-cell ALL and one boy (12.5%) aged 10 years with B-cell ALL. The remaining four patients (50%) were two girls aged 6 and 6 1/2 years and two males aged 10 and 21 years who had lymphocytic leukaemia of the Null-cell class. These results from a tropical environment agree with previous findings among Caucasians with respect to the age and sex incidence and predominance of ALL with Null cells.
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