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  • Title: DNA binding properties of a mutant T antigen from the simian virus 40-transformed human cell line simian virus 80.
    Author: Gruss C, Baumann E, Knippers R.
    Journal: J Virol; 1984 Jun; 50(3):943-6. PubMed ID: 6328024.
    Abstract:
    We investigated whether the T antigen of the simian virus 40-transformed human cell line simian virus 80 ( SV80 ) specifically recognizes DNA sequences of its own template, i.e, the viral sequences integrated in the SV80 cellular genome. In vitro DNA binding experiments clearly indicated that, in contrast to wild-type T antigen, SV80 T antigen does not specifically bind to sites on the integrated viral DNA in SV80 cells.
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