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  • Title: Diarrhea in one to three week-old piglets associated with Clostridium perfringens type A.
    Author: Nabuurs MJ, Haagsma J, Van de Molen EJ, Van der Heijden PJ.
    Journal: Ann Rech Vet; 1983; 14(4):408-11. PubMed ID: 6329060.
    Abstract:
    Investigation on the aetiology of diarrhoea in piglets of one to three weeks of age revealed high numbers of Clostridium perfringens type A in intestinal contents of severely affected animals. Experimental infections with hysterectomy derived, colostrum deprived piglets performed in an isolator resulted in a clinical picture indistinguishable from the clinical signs observed under field conditions i.e. creamy diarrhoea, emaciation, abundant gas in the gut but usually low mortality rate. The predominant post-mortem findings were the presence of gas in the intestinal lumen and in the mucosa, superficial necrosis and villus atrophy.
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