These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: (+)-Tubocurarine blocks the Ca2+-dependent K+-channel of the bullfrog sympathetic ganglion cell.
    Author: Nohmi M, Kuba K.
    Journal: Brain Res; 1984 May 28; 301(1):146-8. PubMed ID: 6329438.
    Abstract:
    (+)-Tubocurarine [+)-Tc: 10-100 microM) reduced the duration of the afterhyperpolarization, which was induced by the activation of Ca2+-dependent K+-conductance (GK,Ca) following an action potential in the bullfrog sympathetic ganglion cell, but did not affect the maximum rates of rise and fall of Na+- and Ca2+-dependent action potentials. The amplitudes of slow rhythmic membrane hyperpolarizations produced by rhythmic rises in the GK,Ca were also decreased by (+)-Tc without a change in their intervals. Thus, (+)-Tc appears to block the Ca2+-dependent K+-channel of the bullfrog sympathetic ganglion cell.
    [Abstract] [Full Text] [Related] [New Search]