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  • Title: Humoral and cellular immune mechanisms in children with spastic bronchitis.
    Author: Prusek W, Wieczorek E, Podwysocka M, Agopsowicz T.
    Journal: Arch Immunol Ther Exp (Warsz); 1984; 32(2):167-76. PubMed ID: 6333227.
    Abstract:
    Twenty children with spastic bronchitis were examined to determine T and B lymphocytes, serum immunoglobulins and the presence of antibodies against autologous lymphocytes. T lymphocytes and B lymphocytes with surface IgA were observed to decrease while B lymphocytes with surface IgG increased. Besides, the level of serum A immunoglobulins was elevated but antibodies against autologous lymphocytes were not detected. In 7 severe cases Levamisol was applied. The treatment appeared effective in 6 children. Clinical improvement was accompanied by substantial alterations in the behaviour of the examined elements of the immunological system, i.e. increase of T and B lymphocytes, increased concentration of serum IgM in 5 and IgA in 4 patients.
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