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  • Title: A study of regional cerebral blood flow and hemodynamics in cerebrovascular diseases by selective continuous infusion of Kr-81m.
    Author: Higa T, Tanada S, Taki W, Fukuyama H, Fujita T, Horiuchi KS, Minato K, Hamanaka D, Odori T, Yonekawa Y.
    Journal: Radiat Med; 1983; 1(2):137-45. PubMed ID: 6333699.
    Abstract:
    A tomographic study of regional cerebral blood flow and hemodynamics was performed on 25 patients with cerebrovascular diseases by selective continuous infusion of krypton-81m (Kr-81m). Kr-81m single photon emission computed tomograms were superimposed on X-ray computed tomograms to assess topographically the perfusion of the entire brain. Study of cerebrovascular diseases using this method showed: (1) regional cerebral blood flow change; (2) perfusion distribution change; (3) the route by which blood reached the brain or the obstructed artery proximal to the circle of Willis; (4) development of a collateral system and its actual function; and (5) efficacy of surgical bypass after extracranial-intracranial anastomosis. This method is especially useful in hemodynamic assessment in patients with ischemic cerebrovascular disease.
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