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  • Title: [Synthesis and antiphlogistic, antipyretic and analgesic properties of 5-benzisothiazolylalkanoic acids and their functional derivatives].
    Author: Vicini P, Amoretti L, Morini G, Impicciatore M.
    Journal: Farmaco Sci; 1984 Oct; 39(10):817-29. PubMed ID: 6334616.
    Abstract:
    A new series of 3-methoxy-1,2-benzisothiazol-5-ylacetic acid analogs and some of their functional derivatives were synthesized and tested for their analgesic, antipyretic and anti-inflammatory activities. From an analysis of the relationship between structure and pharmacological activity, it was observed that modifications in the acid group induced useful variations in the parameters studied.
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