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Title: In vitro production of azide mutagenic metabolite in Arabidopsis, Drosophila and Neurospora. Author: Rosichan JL, Owais WM, Kleinhofs A, Nilan RA. Journal: Mutat Res; 1983 Mar; 119(3):281-5. PubMed ID: 6338378. Abstract: The ability of Arabidopsis, Drosophila and Neurospora to convert azide to its mutagenic metabolite was investigated. Cultures of these organisms all contained significant levels of O-acetylserine sulfhydrylase activity. Extracts from each organism produced a product from O-acetylserine and azide in vitro which was mutagenic in Salmonella typhimurium TA1530.[Abstract] [Full Text] [Related] [New Search]