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  • Title: In vitro activity of ceftazidime (GR 20263) and other beta-lactam antibiotics against Haemophilus influenzae.
    Author: Piot P, Van Dyck E, Colaert J.
    Journal: Infection; 1983; 11 Suppl 1():S32-4. PubMed ID: 6339415.
    Abstract:
    Minimal inhibitory concentrations (MIC) and minimal bactericidal concentrations (MBC) were determined for ceftazidime (GR 20263 - pentahydrate), RO 13-9904, cefoperazone, cefotaxime, lamoxactam, cefamandole and ampicillin using clinical isolates of beta-lactamase-producing and beta-lactamase-negative Haemophilus influenzae. RO 13-9904 and cefotaxime were the most active, followed by ceftazidime, lamoxactam and cefoperazone. Ceftazidime displayed high stability against the beta-lactamase-producing strains with a low MBC:MIC ratio.
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