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  • Title: Urokinase therapy for thrombosis of tricuspid prosthetic valve.
    Author: Joyce LD, Boucek M, McGough EC.
    Journal: J Thorac Cardiovasc Surg; 1983 Jun; 85(6):935-7. PubMed ID: 6343730.
    Abstract:
    A 16-month-old child was born with pulmonic stenosis and a hypoplastic right ventricle. After palliative procedures, the patient began having signs of tricuspid insufficiency and stenosis necessitating a tricuspid valve replacement. A St. Jude Medical valve was implanted. While the child was on aspirin therapy, thrombus formation resulted in valve dysfunction. This thrombus was successfully dissolved with urokinase infusion, and normal valve function was restored.
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