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  • Title: The prophylactic treatment of bronchial asthma in children with ketotifen: a double-blind comparison with placebo.
    Author: Spicak V.
    Journal: J Int Med Res; 1983; 11(3):173-8. PubMed ID: 6347749.
    Abstract:
    Report on a double-blind parallel group comparison of ketotifen and placebo in two groups of twenty-five children with extrinsic bronchial asthma. Duration of treatment: 12 weeks, dosage adapted to body-weight, 0.5-1 mg b.i.d. Main parameters: Overall assessment of efficacy by the treating physician, total duration and frequency of asthmatic episodes per observation period. In all parameters ketotifen was far superior to placebo in spite of decreased concomitant bronchodilator therapy. The tolerance and acceptability of the compound was good.
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