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  • Title: Changes in hexokinase isoenzymes in regions of rat brain during insulin-induced hypoglycemia.
    Author: Kaur G, Singh R, Baquer NZ.
    Journal: J Neurochem; 1983 Aug; 41(2):594-6. PubMed ID: 6348212.
    Abstract:
    Activities of hexokinase isoenzymes were determined during insulin-induced hypoglycemia in soluble and total particulate fractions from three regions of rat brain. Type I hexokinase isoenzyme activity showed a small decrease in both soluble and particulate fractions from the cerebral hemispheres. In cerebellum and brain stem, however, Type I isoenzyme showed a decrease only in the soluble fraction. A significant increase was observed in hexokinase Type II isoenzyme from both the fractions, in all the three brain regions 1 h after insulin administration.
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