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  • Title: [Effect of hydrocortisone on the ribonucleic acid biosynthesis in the liver mitochondria, heart and spleen of rats with alloxan diabetes].
    Author: Minchenko AG.
    Journal: Probl Endokrinol (Mosk); 1978; 24(1):64-8. PubMed ID: 634950.
    Abstract:
    Mitochondrial RNA biosynthesis in diabetic rats under the influence of hydrocortisone (0.5 or 2 U per 100 g for 7 days) increased in the liver and decreased in the spleen. Heart mitochondrial RNA biosynthesis increased after hydrocortisone injection in a dose of 0.5 U per 100 g, but decreased after hormone administration in a dose of 2.5 U per 100 g. Thus, hydrocortisone played an important role in the changes of RNA biosynthesis in the liver, heart, and spleen mitochondria of diabetic animals.
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