These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Degenerative changes and detection of plasminogen in fetal membranes that rupture prematurely.
    Author: Jenkins DM, O'Neill M, Mattar M, France VM, Hsi BL, Faulk WP.
    Journal: Br J Obstet Gynaecol; 1983 Sep; 90(9):841-6. PubMed ID: 6351898.
    Abstract:
    Amniochorion obtained at caesarean section and vaginal delivery, at 34-36 weeks gestation and at term, have been studied by electron microscopy and immunofluorescence for evidence of amniotic epithelial degenerative changes and the presence of plasminogen. When delivery was by caesarean section between 34-36 weeks, electron microscopy revealed no degenerative changes in four cases, but in two cases they were widespread. All but one membrane obtained at term showed only minimal amniotic epithelial cell degenerative changes, but extensive change was seen when delivery was premature after premature membrane rupture. Plasminogen was seen in amniotic epithelium proportional to the degree of cell degeneration; it was absent from healthy membranes. These findings demonstrate that degenerative changes are extensively present in membranes that rupture prematurely, particularly before the onset of premature labour, and suggest a role for plasminogen in membrane rupture.
    [Abstract] [Full Text] [Related] [New Search]