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  • Title: A multicentre prospective randomized trial comparing ceftazidime with cefazolin/tobramycin in the treatment of hospitalized patients with non-pneumococcal pneumonia.
    Author: Mandell LA, Nicolle LE, Ronald AR, Duperval R, Robson HG, Feld R, Vincelette J, Fong I.
    Journal: J Antimicrob Chemother; 1983 Jul; 12 Suppl A():9-20. PubMed ID: 6352661.
    Abstract:
    A multicentre prospective randomized control trial was done to compare the efficacy and toxicity of ceftazidime with that of cefazolin/tobramycin in the treatment of hospitalized patients with non-pneumococcal pneumonia. The results for 50 patients are reported in this paper; 24 in the ceftazidime group and 26 in the cefazolin/tobramycin group. Measurements of clinical response show no differences between the two groups: the same is true for bacteriological response. Minimal toxicity was seen with both treatment groups. The results support the use of ceftazidime as single-drug treatment of hospitalized patients with pneumonia.
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