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  • Title: [Clinical studies on T-1982 (cefbuperazone) in the field of obstetrics and gynecology].
    Author: Chimura T, Oda T, Ozeki K, Mitsui T.
    Journal: Jpn J Antibiot; 1983 May; 36(5):925-31. PubMed ID: 6352986.
    Abstract:
    Clinical studies on T-1982 (cefbuperazone) were performed in 20 patients of obstetrics and gynecology, and the following results were obtained. Clinical effect: The effectiveness was 100% (excellent in 5 cases, good in 4 cases) in intrauterine infection, 75% in adnexitis (excellent in 1 case, good in 2 cases, poor in 1 case), 100% in pelveoperitonitis (excellent in 2 cases, good in 2 cases), 0% in parametritis (poor in 1 case) and 100% in Bartholin's abscess (good in 2 cases), with the overall effectiveness rate of 90% (excellent in 8 cases, good in 10 cases, poor in 2 cases). Bacteriological effect: A total of 17 strains was isolated from 12 out of 20 cases. Fourteen out of 17 strains were aerobic organisms (7 of E. coli, 4 of Klebsiella, 2 of S. faecalis and 1 of S. epidermidis) and 3 out of 17 strains were anaerobes (each 1 strain of B. fragilis, P. prevotii and P. anaerobius) and all of them were eliminated. No side effects due to this drug were noted.
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