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  • Title: [Immunohistological studies on the identification of T cells and T cell subsets infiltrating in human stomach cancer tissues].
    Author: Kasai K, Imamura M, Hiratsuka H, Usui T, Kamiya H, Muroya K, Narimatsu H, Minase A, Totsuka M, Kikuchi K.
    Journal: Gan No Rinsho; 1983 Aug; 29(9):981-6. PubMed ID: 6352990.
    Abstract:
    T cells and T cell subsets in human gastric cancer tissues were identified using the immunoperoxidase technique with anti-T cell monoclonal antibodies (Leu-1, Leu-2, Leu-3 and Leu-4), anti-HLA-DR(Ia) monocronal antibody, and anti-Ig sera. The majority of lymphocytes infiltrating into gastric cancer tissues were Leu-1 and Leu-4 positive T cells; they consisted of a Leu-2 positive T cell subset (Tc/s) and a Leu-3 positive T cell subset (Th/i). Leu-2 positive T cells infiltrated the gastric cancer tissues of 6 patients with a moderate or marked degree of lymphocyte infiltration; Leu-3 positive T cells infiltrated these tissues of 11 patients. These results show that the degree of T cell and T cell subset infiltration may effect the host-tumor relationship.
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