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  • Title: Intestinal K99+ escherichia coli adhesion and absorption of colostral IgG1 in the newborn lamb: effect of fetal infusion of thyroid hormones.
    Author: Cabello G, Levieux D, Girardeau JP, Lefaivre J.
    Journal: Res Vet Sci; 1983 Sep; 35(2):242-4. PubMed ID: 6356258.
    Abstract:
    Continuous infusion of thyroid hormones during the last 12 days of gestation in ovine fetuses was associated with: a reduction of the rate of appearance of blood IgG1 after colostrum feeding in the newborn lambs; an important reduction of the number of jejunal cells filled with IgG1, 12 hours post partum, suggesting a premature closure of the intestinal permeability to IgG1; and a significant reduction of the K99+ Escherichia coli adhesion on the intestinal villi. These results could partly explain relationships observed previously between perinatal thyroid function abnormalities and the occurrence of neonatal diseases.
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