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  • Title: Cytoprotection and 6-keto-prostaglandin-F1 alpha.
    Author: Bálint GA, Varró V.
    Journal: Acta Physiol Hung; 1983; 61(4):233-5. PubMed ID: 6359818.
    Abstract:
    Several prostaglandins were found to protect the gastric mucosa against the ulcerogenic effect of immobilization (stress) and of indomethacin in the rat. The analogue 6-keto-prostaglandin-F1 alpha had no cytoprotective effect in the same region and even seemed to facilitate ulceration in the stomach in a dose-dependent manner. Unusually high doses of this prostaglandin analogue also exerted a slight cytoprotective effect.
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