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  • Title: Long-term clinical evaluation of suprofen and aspirin in patients with osteoarthritis.
    Author: Willkens RF.
    Journal: Pharmacology; 1983; 27 Suppl 1():48-54. PubMed ID: 6361791.
    Abstract:
    The safety and efficacy of suprofen 200 mg q.i.d. and aspirin 650 mg q.i.d. in the treatment of chronic pain due to osteoarthritis were compared in a double-blind, randomized, parallel group study over a 12-week period. Suprofen was comparable to aspirin in the relief of pain and improvement in activity impairment. Results of ocular examination, laboratory data, and vital signs examinations indicated no clinically significant changes for suprofen. No serious side effects were reported by either group.
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