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  • Title: The effect of miconazole on ergosterol-less mutant of Candida albicans.
    Author: Pesti M, Becher D, Bartsch G.
    Journal: Acta Microbiol Hung; 1983; 30(1):25-9. PubMed ID: 6362313.
    Abstract:
    The effect of miconazole in fungistatic concentration on an ergosterol-competent Candida albicans strain and its ergosterol-nonproducing mutant was investigated by scanning and transmission electron microscopy. The ergosterol-less mutant showed pronounced alterations by scanning electron microscopy. The increased sensitivity to miconazole of the ergosterol-less mutant was attributed to an altered plasma membrane composition and rigidity.
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