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  • Title: Combination chemotherapy in metastatic or recurrent non-small cell bronchogenic carcinoma. 5-year results.
    Author: Ojala A, Nikkanen VN, Paloheimo S, Palojoki A, Thölix E.
    Journal: Strahlentherapie; 1983 Dec; 159(12):775-7. PubMed ID: 6364459.
    Abstract:
    A controlled clinical trial was performed to test two different chemotherapy regimens (doxorubicin + cyclophosphamide + vincristine versus CCNU + vincristine) in 100 patients with metastatic or recurrent non-small cell bronchogenic carcinoma. There was no significant difference between treatment groups in survival or in response. Only 4 patients had a partial remission and there were no complete responders. Median survival was 7 months and 8 patients lived over two years, one patient is still alive (65 + months). The benefit of combined chemotherapy in non-small cell bronchogenic carcinoma remains minimal.
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