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  • Title: Major histocompatibility complex restriction and transplantation immunity. A possible solution to the allograft problem.
    Author: Silvers WK, Bartlett ST, Chen HD, Fleming HL, Naji A, Barker CF.
    Journal: Transplantation; 1984 Jan; 37(1):28-32. PubMed ID: 6364484.
    Abstract:
    Studies of the survival of weakly histoincompatible skin grafts in which the Langerhans' cells (LC)5 have been replaced with major histocompatibility complex (MHC)-compatible or incompatible LC, as well as studies of the fate of cultured endocrine allografts in MHC-compatible and incompatible mice and rats, indicate that allografts are only recognized as foreign if they possess donor macrophages (or cells of this family), or if antigen presenting cells MHC-compatible with the graft can be provided by the host.
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