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  • Title: Tolerance and the H-Y antigen: Requirement for male T cells, but not B cells, to induce tolerance in neonatal female mice.
    Author: Weissman IL, Jerabek L, Greenspan S.
    Journal: Transplantation; 1984 Jan; 37(1):3-6. PubMed ID: 6364485.
    Abstract:
    Transplantation tolerance of the H-Y antigen may be induced and transferred by lymphoid cells, but not by nonlymphoid cells. In this study we have demonstrated that amongst lymphoid cells, T cells--but not B cells or macrophages--are capable of inducing transplantation tolerance. In contrast, all three populations express sufficient amounts of immunogenic H-Y antigen to sensitize adult female mice to a subsequent male skin graft, as demonstrated by the second-set reaction.
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