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  • Title: [Neurologic adverse manifestations and complications of ambulatory therapy with psychotropic drugs in the late stages].
    Author: Makeeva VL.
    Journal: Zh Nevropatol Psikhiatr Im S S Korsakova; 1978; 78(2):178-82. PubMed ID: 636711.
    Abstract:
    Neurological side-effects and complications were studied in 100 patients having undergone long-term (3--14 years) out-patient treatment. In 14 cases there were slight side-effects. In patients of old age, after 6 year lithium treatment there were extrapyramidal signs, disturbances of memory and disorders of orientation in place. In 1 case following 2 year treatment with small doses of neuroleptical drugs there was an oral dyskinesia, after which an overdosage with antidepressive drugs and tranquillizers led to an akineticohypotonic syndrome. The side-effects and complications had a reversible character. Recommendations for therapy of such complications are given.
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