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  • Title: Comparative effects of propranolol and prazosin upon serum lipids in thiazide- treated hypertensive patients.
    Author: Johnson BF, Romero L, Johnson J, Marwaha R.
    Journal: Am J Med; 1984 Feb 27; 76(2A):109-12. PubMed ID: 6367445.
    Abstract:
    Earlier reported thiazide-induced changes in serum lipid concentrations were confirmed with increased triglyceride and total cholesterol levels. However, lipoprotein cholesterol ratios were unchanged. Propranolol caused further increases in triglyceride and very low-density lipoprotein cholesterol, and lowered high-density lipoprotein cholesterol and the high-density lipoprotein:total cholesterol ratio. With the addition of prazosin to the polythiazide regimen, there was a significant increase in serum high-density lipoprotein cholesterol when compared with the placebo.
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