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  • Title: Malakoplakia mimicking carcinoma metastatic to lung.
    Author: Crouch E, White V, Wright J, Churg A.
    Journal: Am J Surg Pathol; 1984 Feb; 8(2):151-6. PubMed ID: 6367503.
    Abstract:
    Malakoplakia is a rare inflammatory disorder which infrequently involves sites outside of the lower genitourinary or gastrointestinal tract. We report a case of malakoplakia in which the patient presented with a left renal mass and bilateral pulmonary nodules suggestive of metastatic renal carcinoma. Postmortem cultures of the lesions grew E. coli; macrophages at both sites contained gram-negative bacilli and numerous Michaelis-Gutmann bodies. X-ray spectroscopic analysis of the bodies showed wide variation in calcium, phosphorus, and iron content, suggesting that Michaelis-Gutmann bodies were formed in part by the deposition of amorphous salts.
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