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  • Title: Distribution of T-cell subsets as defined by monoclonal antibodies in skin lesions of psoriasis vulgaris.
    Author: Kaudewitz P, Braun-Falco O, Kind P, Galosi A, Rieber P, Riethmüller G.
    Journal: Arch Dermatol Res; 1984; 276(1):33-5. PubMed ID: 6367674.
    Abstract:
    Cryostat tissue sections from skin lesions of 16 patients suffering from chronic stationary psoriasis vulgaris were assayed for the presence of distinct T-cell subpopulations with monoclonal antibodies. Using two pan-T surface markers (M-T 4-11 and Lyt 3) the total number of infiltrating T-cells was measured. This cell population was further dissected into Leu 3a (helper/inducer) and M-T 8-11 (cytotoxic/suppressor) positive subsets. Percentages of T-cell subpopulations were within the ranges found in healthy peripheral blood and were thus regarded as normal.
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