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  • Title: Additional antacid does not increase the effect of cimetidine in gastric ulcer disease.
    Author: Rune SJ, Jensen KG, Wulff HR, Bendtsen F, Lindskov J, Mejer J, Højlund M, Nissen VR, Willumsen L, Agner E.
    Journal: Scand J Gastroenterol; 1984 Jan; 19(1):56-8. PubMed ID: 6369522.
    Abstract:
    Eighty-one adult outpatients with endoscopically confirmed gastric ulceration were treated with cimetidine (1 g/day). In addition, the patients were allocated at random to either intensive antacid treatment or placebo treatment. This part of the study was double-blind. It was found that additional antacid treatment had no effect on ulcer healing and symptoms in cimetidine-treated gastric ulcer patients. The results were similar in patients with corpus ulcers and patients with prepyloric ulcers.
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