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  • Title: Genital herpes simplex virus infections in adults.
    Author: Mertz G, Corey L.
    Journal: Urol Clin North Am; 1984 Feb; 11(1):103-19. PubMed ID: 6369699.
    Abstract:
    With the decline in prevalence of childhood-acquired oral-labial herpes simplex type 1 infections in some populations and the increasing incidence of genital herpes infections in adults, clinicians are more likely to see patients with severe primary, first-episode genital herpes infections. Complications of these primary infections may include aseptic meningitis and urine retention secondary to sacral radiculopathy or autonomic dysfunction. Presented are the clinical course of first-episode and recurrent infections, complications, diagnostic laboratory methods, and results of controlled clinical trials evaluating the efficacy of topical, intravenous, and oral preparations of acyclovir.
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